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Is It Possible to be Allergic to Water?

Written by: Nisha Evangelista


Short Answer: Yes!




Introduction

Aquagenic urticaria is an exceedingly rare and perplexing skin condition where exposure to water triggers hives and itching. This unusual allergy poses significant challenges to daily activities, given water's ubiquitous presence. Understanding this condition is crucial for developing effective management strategies and improving the quality of life for those affected.

Causes and Mechanism

According to the Allergy & Asthma network, “the exact cause of aquagenic urticaria is unknown”. However, there have been a few theories behind the causes of this condition including: 

  • Histamine Release: Contact with water may cause skin cells to release histamine, leading to hives and itching. 

  • Interaction with Skin Substances: Water may dissolve certain substances on or in the skin, triggering an immune response.

  • Temperature Sensitivity: The temperature of the water might play a role, although reactions typically occur with water at any temperature.

  • Genetic Factors: Some cases suggest a potential hereditary component, though evidence is limited due to the rarity of the condition.

Symptoms

Symptoms of aquagenic urticaria typically manifest quickly after water exposure and include:

  • Hives: Small, red, and itchy wheals appear on the skin areas in contact with water.

  • Itching and Burning: Affected areas may experience intense itching or burning sensations.

  • Duration: Symptoms usually resolve within 30 to 60 minutes after drying off.

  • Systemic Reactions: Rarely, individuals may experience more severe reactions like wheezing or difficulty breathing, especially with extensive water exposure.

Diagnosis

Diagnosing aquagenic urticaria involves a careful evaluation:

  1. Clinical History: Detailed discussion about symptom onset, duration, and triggers.

  2. Water Challenge Test: Applying water to the skin under controlled conditions to observe reactions.

Treatment and Management

Managing aquagenic urticaria focuses on symptom relief and preventing reactions:

  • Antihistamines: Regular use can help control hives and itching. Doctors prefer second generation H1 antihistamines such as cetirizine (Zyrtec) or loratadine (Claritin) (Source: Healthline.com)

  • Barrier Creams: Applying oils or creams before water exposure may create a protective layer on the skin.

  • Short and Infrequent Exposure: Limiting the duration and frequency of water contact can reduce symptom severity.

  • Temperature Control: Some individuals find that using water at certain temperatures minimizes reactions.

  • Phototherapy: In some cases, controlled exposure to ultraviolet light has shown improvement in symptoms. 

  • Epinephrine Auto-Injectors: For those prone to severe reactions, carrying an epinephrine injector is advisable.

There are other options available including treatments such as the biologic omalizumab, steroid medications, or selective serotonin reuptake inhibitors (SSRIs).2

Psychological and Social Impact

Living with aquagenic urticaria can have significant psychological and social implications:

  • Daily Challenges: Routine activities like bathing, swimming, or going out in the rain become problematic.

  • Emotional Stress: The condition can lead to anxiety, depression, and social isolation.

  • Support Systems: Counseling and support groups can be beneficial in coping with the emotional burden.


Conclusion

Aquagenic urticaria presents unique and significant challenges due to its rare and unusual nature. Comprehensive understanding and effective management strategies are vital for improving the lives of those affected. Ongoing research holds promise for better treatments and possibly uncovering the underlying causes of this mysterious condition.


Sources:


disclaimer: Everything posted on our website and Instagram is intended for basic educational purposes only. If you suspect you have symptoms of any condition, it is essential to consult a dermatologist or your healthcare provider for a proper diagnosis and treatment plan. Our content is not a substitute for professional medical care.


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